Two Golden Chalice presentations were made in the Grand Commandery of the Knights Templar of Pennsylvania within Pittsburgh Commandery No. 1 and Duquesne Commandery No. 72.
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This Sword was in recognition of SK Rossman’s donating to the Grand Masters Club completing Tier 5 with a total of 25 Grand Masters Clubs totaling $25,000 in contributions. In reaching 25 Grand Masters Clubs the Knights Templar Eye Foundation automatically recognizes this great accomplishment by awarding a Sword of Merit. SK Rossman donated an additional $10,000 contribution for the Golden Chalice which was to honor his wife.
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In a cohort of COD/CRD patients, they will combine the cutting-edge short and long-read wholegenome sequencing to investigate the noncoding and structural genetic variants, which are both often missed by current Sanger sequencing and capture-sequencing technologies. The genetic testing pipeline which will be built in this study may also be used to study other genetic diseases in the future.
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On April 4, 2022, SK David Studley, Grand Captain General of The Grand Encampment who is also the Grand Commander of California, and Trustee of the Knights Templar Eye Foundation presented a Sword of Merit on behalf of the Knights Templar Eye Foundation during a reception honoring SK Studley at Marysville Commandery No. 7, receiving the sword was SK Stephan Parnow, Commander of Marysville Commandery.
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Our meeting ended with twenty-two Competitive Renewal & Career Starter grants for a total of $1,533,025 that were recommended by the SAC doctors and later that night approved by the KTEF SAC committee.
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The significance of this scientific direction is highlighted by the fact that numerous blindness-causing mutations, in addition to those in PRCD, that affect children are associated with accumulation of extracellular vesicles in the retina. Therefore, addressing the cellular and molecular mechanisms underlying their formation and clearance are key steps in developing future therapeutic strategies.
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Childhood glaucoma is a pediatric condition leading to significant visual impairment. Juvenile-onset primary open angle glaucoma (JOAG) is a subtype of primary glaucoma, and the disease presents from four years to early adulthood. The disease is identified by increased pressure within the eye and progressive death of neurons in the back of the eye, which can eventually lead to blindness in children.
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The fovea is a specialized retinal area that enables high-acuity vision, and we use it to detect fine spatial details and colors. In mammals, only humans and some primates have a fovea, but we know relatively little about how the fovea is formed.
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By studying these changes over time with and without the drug, we will begin to understand the cellular and metabolic mechanisms responsible for this devastating group of diseases that cause childhood blindness. These studies will move us closer to developing a novel drug capable of treating vision loss in this diverse set of inherited diseases regardless of gene mutation.
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On January 12, 2022, SK Michael Daniels, Right Eminent Past Grand Commander of the Grand Commandery of North Carolina presented a Sword of Merit on behalf of the Knights Templar Eye Foundation during the stated meeting of Nazareth Commandery No. 41 to SK D. Trent Carter, Eminent Commander of Nazareth Commandery
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It is with great sadness that we announce the passing of Most Eminent Past Grand Master William Jackson Jones, GCT, on January 31, 2022. He was a true Masonic Christian Gentleman who will be greatly missed by his family, Masonic and Templar family, dental patients, and community.
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Over the last year, Dr. Meier has successfully developed a way of quickly measuring the specific neural deficits that underlies an individual’s poor vision. She plans to use this same task in children, while recording brain responses over time. Her long-term aim is to develop a way of measuring brain responses in young pre-verbal children. Once they know a child’s specific neural deficits, clinicians can generate individualized treatments that target his or her specific pattern of neural abnormalities – resulting in faster and better treatment.
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The proposed study presents a unique opportunity to gain new insights into the establishment of a functional retinal network but also identify new regulatory signaling events allowing us to modulate blood vessel growth essential for alternative therapies such as ROP. 3
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Understanding this causal sequence is critical to developing treatments that address the cause(s) of juvenile myopia, not just the symptoms as current treatments do. This is extremely important because myopia is estimated to affect 30% of the world’s population already (the cost in the US alone being $4 billion a year) and will affect 50% of the world’s population by 2050.
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Dr. Hwang hopes that our research will lead to new ways to prevent childhood blindness in Stickler syndrome.
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Dr. Gamuyao is researching the ANXA3 protein is a novel regulator of abnormal pathologic blood vessels in the retina and is a promising target for ROP treatment. Despite its emerging importance, the information on the role and mechanism of ANXA3 in ROP is still inadequate.
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The long-term goal of this proposal is to discover new regulatory mechanisms to provide therapeutic targets and drugs in the adult brain for recovery from Amblyopia.
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Currently, Grand Master’s Club donors receive a plaque, lapel pin, and a Crusaders Cross up to the first five Grand Masters Clubs. However, many of our members have asked the foundation to make a change to the Jewel. Because of these requests, the Jewel now includes five tiers with five levels within each tier, each tier has a different colored center but still has quadrants representing the different levels.
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This study will establish ceramide as a potentially important therapeutic target for RP and ways to lower ceramide levels as a possible therapeutic strategy for other retinal diseases.
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The Children's Eye Foundation of the American Association for Pediatric Ophthalmology and Strabismus (CEF of AAPOS) is extremely grateful to the Knights Templar Eye Foundation (KTEF) for their transformative investment in Stop Infant Blindness in Africa (SIBA).
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